Laboratuvar testleri, kullan\u0131lmam\u0131\u015f e-likitlerin do\u011fal olarak a\u011f\u0131r metal i\u00e7ermedi\u011fini g\u00f6steriyor. Nikel, krom ve kur\u015fun gibi metallerin eser miktarlar\u0131 aerosol olu\u015fumu s\u0131ras\u0131nda \u0131s\u0131t\u0131c\u0131 coil\u2019lerden buhara ge\u00e7ebilse de ba\u011f\u0131ms\u0131z toksikolojik analizler, bu konsantrasyonlar\u0131n genellikle belirlenmi\u015f farmas\u00f6tik ve i\u015f sa\u011fl\u0131\u011f\u0131 g\u00fcvenli\u011fi e\u015fiklerinin olduk\u00e7a alt\u0131nda kald\u0131\u011f\u0131n\u0131 g\u00f6steriyor.<\/p>\n\n
Haber ba\u015fl\u0131klar\u0131, elektronik sigara buhar\u0131n\u0131n kullan\u0131c\u0131lar\u0131 kur\u015fun, nikel ve krom gibi zehirli a\u011f\u0131r metallerin tehlikeli seviyelerine maruz b\u0131rakt\u0131\u011f\u0131<\/a> y\u00f6n\u00fcnde s\u0131k s\u0131k uyar\u0131larda bulunuyor. Metal toksisitesi ger\u00e7ek bir t\u0131bbi endi\u015fe olsa da toksikologlar ve solunum hastal\u0131klar\u0131 uzmanlar\u0131, eser miktardaki kimyasal elementlerin tespit edilmesinin ger\u00e7ek ya\u015famda klinik zarar\u0131n kan\u0131tlanmas\u0131ndan temelden farkl\u0131 oldu\u011funu vurguluyor.<\/p>\n\n Tehlikenin varl\u0131\u011f\u0131 ile ger\u00e7ek toksik maruziyet aras\u0131ndaki fark\u0131 anlamak i\u00e7in vape donan\u0131m\u0131n\u0131n nas\u0131l \u00e7al\u0131\u015ft\u0131\u011f\u0131n\u0131, hakemli ara\u015ft\u0131rmalar\u0131n insan kullan\u0131c\u0131larla ilgili bulgular\u0131n\u0131 ve ulusal mevzuat \u00e7er\u00e7evelerinin \u00fcr\u00fcn g\u00fcvenli\u011fini nas\u0131l denetledi\u011fini incelemek gerekir.<\/p>\n\n Saf e-likit<\/a> form\u00fclleri bitkisel gliserin, propilen glikol<\/a>, farmas\u00f6tik safl\u0131kta nikotin ve g\u0131da s\u0131n\u0131f\u0131 aroma vericilerden olu\u015fur. Ba\u011f\u0131ms\u0131z kimyasal analizler, ticari e-likitlerin \u015fi\u015felenmi\u015f h\u00e2llerinde a\u011f\u0131r metal i\u00e7ermedi\u011fini do\u011fruluyor. Metal ge\u00e7i\u015fi bunun yerine atomizer i\u00e7indeki fiziksel a\u015f\u0131nma ve termal stres yoluyla ger\u00e7ekle\u015fiyor.<\/p>\n\n Elektronik sigara \u00e7al\u0131\u015ft\u0131r\u0131ld\u0131\u011f\u0131nda metal diren\u00e7 teli, likitle \u0131slanm\u0131\u015f fitili \u0131s\u0131t\u0131r. Tekrarlanan \u0131s\u0131tma d\u00f6ng\u00fcleri boyunca mikroskobik oksitlenme ve fiziksel a\u015f\u0131nma, k\u00fc\u00e7\u00fck par\u00e7ac\u0131klar\u0131n rezervuardaki likide veya do\u011frudan olu\u015fan aerosole ge\u00e7mesine neden olabilir. Is\u0131tma eleman\u0131n\u0131n bile\u015fimi \u2014\u00e7o\u011funlukla nikel, krom, demir veya daha d\u00fc\u015f\u00fck kalite paslanmaz \u00e7elik i\u00e7eren ala\u015f\u0131mlardan \u00fcretilir\u2014 testlerde hangi eser elementlerin g\u00f6r\u00fclece\u011fini belirler.<\/p>\n\n Kamuoyundaki endi\u015felerin b\u00fcy\u00fck b\u00f6l\u00fcm\u00fc, Johns Hopkins Bloomberg Halk Sa\u011fl\u0131\u011f\u0131 Fak\u00fcltesi taraf\u0131ndan y\u00fcr\u00fct\u00fclen ve g\u00fcnl\u00fck 56 kullan\u0131c\u0131n\u0131n cihazlar\u0131n\u0131 inceleyen 2018 tarihli bir ara\u015ft\u0131rmadan<\/a> kaynaklan\u0131yor. Ara\u015ft\u0131rmac\u0131lar aerosol \u00f6rneklerinde \u00f6l\u00e7\u00fclebilir miktarlarda krom, nikel ve kur\u015fun tespit ederek olas\u0131 uzun vadeli sa\u011fl\u0131k risklerine i\u015faret etti.<\/p>\n\n Ancak t\u0131p uzmanlar\u0131, ham verilerin ger\u00e7ek ya\u015famdan klinik ba\u011flamdan yoksun oldu\u011funu savundu. Onassis Kardiyak Cerrahi Merkezi\u2019nde ara\u015ft\u0131rmac\u0131 olan Dr. Konstantinos Farsalinos<\/a>, laboratuvar metodolojisinin insanlar\u0131n vape kullan\u0131m al\u0131\u015fkanl\u0131klar\u0131n\u0131 yans\u0131tmayan, kesintisiz ve yapay \u00e7eki\u015fler uygulad\u0131\u011f\u0131n\u0131 belirtti. \u015eunlar\u0131 s\u00f6yledi:<\/p>\n\n “[\u0130nhalasyon yoluyla al\u0131nan] ila\u00e7lardan kaynaklanan g\u00fcnl\u00fck al\u0131m i\u00e7in FDA s\u0131n\u0131rlar\u0131n\u0131 a\u015fman\u0131z i\u00e7in g\u00fcnde 100 ml’den fazla vape kullanman\u0131z gerekti\u011fini hesaplad\u0131m… \u0130nsanlar g\u00fcnde 17.000’den fazla nefes al\u0131yor, ancak elektronik sigaradan g\u00fcnde yaln\u0131zca 400-600 \u00e7eki\u015f yap\u0131yor.”<\/p>\n<\/blockquote>\n\n Toksikoloji, zehri dozun belirledi\u011fi temel ilkesine dayan\u0131r. Ortam havas\u0131na ili\u015fkin \u00e7evresel g\u00fcvenlik e\u015fikleri, g\u00fcnde 24 saat boyunca kesintisiz ve istemsiz solunumu esas al\u0131r. Bu ortam havas\u0131 \u00f6l\u00e7\u00fctlerini aral\u0131kl\u0131 buhar inhalasyonuna do\u011frudan uygulamak, risk alg\u0131s\u0131n\u0131n \u00e7arp\u0131t\u0131lmas\u0131na yol a\u00e7ar.<\/p>\n\nMetallerin Kayna\u011f\u0131: E-Likit mi, Is\u0131tma Elemanlar\u0131 m\u0131?<\/h2>\n\n
Toksikolojik Ba\u011flam: Maruziyet ve \u0130nhalasyon Yoluyla Al\u0131nan \u0130la\u00e7 S\u0131n\u0131rlar\u0131<\/h2>\n\n
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